Research - UPMC

Research

The concussion program at UPMC has produced several groundbreaking and pioneering studies. Our approach to concussion assessment, treatment, rehabilitation, and education is rooted in evidence-based research found in respected, peer-reviewed journals of medicine. While we’ve published more than 200, here are a few key publications:

A comprehensive, targeted approach to the clinical care of athletes following sport-related concussion
This paper discusses risk and prognostic factors for concussion outcomes, reviews comprehensive approaches to assessment, and describes a new method for conceptualizing treatment for sport-related concussion using clinical experience.

Collins MW, Kontos AP, Reynolds E, Murawski CD, Fu FH. A comprehensive, targeted approach to the clinical care of athletes following sport-related concussion. https://www.ncbi.nlm.nih.gov/pubmed/24337463

A Brief Vestibular/Ocular Motor Screening (VOMS) assessment to evaluate concussions: preliminary findings
This study describes and provides initial data for the internal consistency and validity of a brief clinical screening tool for vestibular and ocular motor impairments and symptoms after sport-related concussions.

Mucha A, Collins MW, Elbin RJ, Furman JM, Troutman-Enseki C, DeWolf RM, Marchetti G, Kontos AP. A Brief Vestibular/Ocular Motor Screening (VOMS) assessment to evaluate concussions: preliminary findings. https://www.ncbi.nlm.nih.gov/pubmed/25106780

Concussion is Treatable: Statements of Agreement from the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting held in Pittsburgh October 15-16, 2015
On October 14–16, 2015, the Targeted Evaluation & Active Management (TEAM) Approaches To Treating Concussion meeting was convened in Pittsburgh, Pennsylvania, USA. 37 concussion experts from neuropsychology, neurology, neurosurgery, sports medicine, physical medicine and rehabilitation, physical therapy, athletic training, and research, and 12 individuals representing sport, military, and public health organizations attended the meeting. The 37 experts indicated their agreement on a series of statements using an audience response system clicker device.

Michael W. Collins, PhD, Anthony P. Kontos, PhD, et al., Concussion is Treatable: Statements of Agreement from the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting held in Pittsburgh October 15-16, 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119544/

Sport-related Concussion Clinical Profiles: Clinical Characteristics, Targeted Treatments, and Preliminary Evidence
Sport-related concussion (SRC) is a heterogeneous injury that involves varied symptoms and impairment that presents a significant clinical challenge to sports medicine professionals. In response to this challenge, clinical researchers have proposed clinical profiles or subtype models for assessing and treating athletes with SRC. One such model emphasizes five concussion clinical profiles including cognitive/fatigue, vestibular, ocular, migraine, and anxiety/mood. Sleep is a common modifier that co-occurs across these clinical profiles. A combination of medical history, risk factors, injury information, clinical characteristics, and assessment outcomes can inform each clinical profile. Preliminary data involving 236 patients from a concussion specialty clinic indicate that the migraine (26%) and anxiety/mood (24%) profiles are the most common, with vestibular and ocular profiles combined representing more than one third (35%) of clinical profiles. Findings also support several relationships among different clinical profiles including vestibular and migraine, suggesting that many athletes present with multiple clinical profiles. Targeted, active treatments for each profile are discussed.

Kontos AP, Sufrinko A, Sandel N, Emami K, Collins MW Sport-related Concussion Clinical Profiles: Clinical Characteristics, Targeted Treatments, and Preliminary Evidence https://www.ncbi.nlm.nih.gov/pubmed/30855306

Recovery Following Sport-Related Concussion: Integrating Pre- and Postinjury Factors Into Multidisciplinary Care
This study aims to update concussion recovery curves by considering pre- and postinjury modifying factors and determine whether there is a dose-response for modifying factors on recovery.

Kontos AP, Elbin RJ, Sufrinko A, Marchetti G, Holland CL, Collins MW Recovery Following Sport-Related Concussion: Integrating Pre- and Postinjury Factors Into Multidisciplinary Care https://www.ncbi.nlm.nih.gov/pubmed/31479086

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